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Diagnosis and Management of Acral Pigmented Lesions

By November 28, 2023July 6th, 2024No Comments

Ingrassia, Jenne P. BA; Stein, Jennifer A. MD, PhD; Levine, Amanda MD; Liebman, Tracey N. MD



Survival outcomes in acral lentiginous melanoma (ALM) are worse than for cutaneous melanoma. Diagnostic delays are believed to contribute to worse outcomes in ALM, including advanced-stage disease at initial presentation. Acral lentiginous melanoma, especially in its early stages, may be difficult to discern from benign pigmented acral lesions.


The purpose of this article is to provide a comprehensive review of the diagnosis and management of acral pigmented lesions.


A literature review was performed. The outcomes included were the clinical and dermoscopic features and the management frameworks and considerations for acquired and congenital melanocytic nevi, acral melanosis, nonmelanocytic pigmented lesions, and ALM.

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