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Clinical and Pathologic Factors in Stage I and II Melanoma Recurrence

By April 28, 2026No Comments

Maya Mundada, BSXiaochen Zhong, BAAlexandra So, BS;

Key Points

 

Question  What demographic, clinical, and pathological characteristics are associated with the time to recurrence of localized melanomas?

Findings  In this cohort study of 1092 individuals diagnosed with stage IA to IIC melanomas, tumor ulceration, thickness, location on the face or scalp or neck compared with the arms, neurotropism, lymphovascular invasion, and presence of mitoses were associated with time to melanoma recurrence in multivariable analysis.

Meaning  Results of this study suggest that factors in addition to melanoma ulceration and thickness provide an important guide for patient surveillance and counseling about potential recurrence.

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